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α- Acetyl group- γ- Production method and application of but

Time:2021-05-20 Source: Yuyuan chemical Click:107

Main uses: it is an important intermediate for the synthesis of vitamin B, and also for the synthesis of 3,4-disubstituted pyridines and 5,4-disubstituted pyridines-( β- Hydroxyethyl) - 4-methylthiazole intermediate.
Production method:
1、 γ- Butyrolactone was synthesized by Claisen condensation with vinyl acetate.
2. Ethyl acetoacetate (or methyl acetoacetate) is prepared by condensation with ethylene oxide.